The influence of cannabis on hormones

Liz Filmer
24 Jun 2025

The effects of cannabis on the endocrine system are becoming increasingly evident. Marijuana can modulate key hormones that regulate female health, fertility, and menopause. Among other functions still under study.


Cannabis and Hormones: the Endocannabinoid System

Cannabinoids interact directly with the endocannabinoid system, a network that influences the body's glands and hormones. Hence its great influence.

Cannabis can act as a modulator in the release and synthesis of hormones such as estrogen and progesterone. These hormones play a crucial role in regulating the menstrual cycle and maintaining bone health in postmenopausal women.

CBD and Cannabis for Bone Health and Estrogen Deficiency

In preclinical studies, Rutgers researchers have shown that CBD may offer benefits against bone loss associated with estrogen deficiency. This hormonal change impacts millions of women after menopause. This opens the door to considering cannabis as a natural support during this stage.

Cannabinoids Regulate Sex Hormones

The relationship between cannabis and sex hormones is bidirectional. On the one hand, cannabis use can alter estrogen and testosterone levels. Furthermore, the body uses endocannabinoids to fine-tune reproductive processes, libido, and emotional stability. As a study in Frontiers in Neuroscience highlights, controlled use can help reduce symptoms such as mood swings, menstrual cramps, and hot flashes.

Menopause and Cannabis: Natural Relief

Hot flashes, insomnia, and irritability are recurring complaints among women going through menopause. A Harvard Health article suggests that more and more women are turning to cannabis to help alleviate these symptoms thanks to its regulating effect on the nervous system and stress hormones.

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Liz Filmer