The Benefits of Cannabis for Mental Health

Liz Filmer
25 Oct 2025

Medical cannabis can help improve mental well-being, promoting calmness and emotional balance. Recent research shows that it can be effective in treating anxiety, depression, and other emotional issues.


A study published in Elsevier found that adults with anxiety and depression who used medical cannabis saw a significant reduction in their symptoms. In just three months, their scores on anxiety and depression tests dropped to non-problematic levels, and these improvements lasted for at least six months.  

Controlled doses of THC (10-15 mg taken orally or 3 puffs from a vaporizer) provided the best short-term and long-term relief. This effect was especially strong for patients who did not improve with typical psychiatric medications, enhancing their quality of life and allowing them to reduce their other medications.  

Studies also reported positive outcomes for sleep issues, PTSD, and overall well-being with both CBD and THC-based cannabis. One trial found that nabilone, a synthetic form of THC, significantly reduced nightmares and improved sleep in patients with PTSD compared to a placebo. Most studies showed that patients tolerated medical cannabis well, with only mild and temporary side effects. 

What is the Endocannabinoid System? 

The endocannabinoid system helps manage emotions and stress. Cannabis affects neurotransmitters like serotonin, dopamine, and GABA, which can help those with mood disorders.  

It’s important to have medical supervision and tailor the doses and types of cannabis (THC/CBD) to each person, since responses can vary. While medical cannabis is not a cure for mental health disorders, it can provide significant and lasting symptom relief, improve quality of life, and enhance daily functioning, with few side effects when used correctly.  

Overall, research shows that medical cannabis is a safe and effective option for improving symptoms of anxiety, depression, insomnia, and emotional stress, especially for people who do not respond well to standard treatments. Personalization, medical guidance, and solid scientific backing are key to using it safely and effectively.

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Liz Filmer