Understanding THCV, CBN, and CBG: The Minor Cannabinoids

Liz Filmer
18 Sep 2025

For years, the conversation about cannabis has primarily focused on THC and CBD. However, the cannabis plant contains over 100 cannabinoids, each offering unique effects and potential benefits. Today, the cannabis community is increasingly exploring THCV, CBN, and CBG and their advantages.


THCV: The Cannabinoid for Energy and Focus

Known as "the energy cannabinoid," THCV (tetrahydrocannabivarin) has a different effect profile than THC. Unlike THC, THCV usually doesn’t produce psychoactive effects at low doses. Its potential benefits include:

Appetite Suppressant: THCV may suppress appetite, leading to its nickname "anti-munchies." 
Antipsychotic Effects: Some research indicates that THCV may have therapeutic potential for the negative and cognitive symptoms of schizophrenia.
Blood Glucose Control: Recent research suggests that THCV may help regulate blood sugar levels, making it a promising area for the treatment of type 2 diabetes.

A crucial fact for users is that THCV’s boiling point is 220°C, which is higher than that of THC. This is important when vaping THCV-rich concentrates, as low temperatures may not effectively activate this cannabinoid.

CBN: A Natural Ally Against Insomnia

CBN (cannabinol) is a cannabinoid that forms as THC degrades over time due to exposure to air and light. This is why older or poorly cured cannabis typically has a high CBN content and creates a more sedative effect.

Although not as potent a sedative as some other compounds, CBN is known for its calming effects. Its main properties include:

Improved Sleep: CBN is highly sought after for combating insomnia.
Anti-Inflammatory Properties: CBN has shown potential in reducing inflammation, which complements its relaxing effects. 
Neuroprotection and Glaucoma: Recent studies suggest CBN may have therapeutic potential for glaucoma by modulating intraocular pressure and protecting neurons. 
Antitumor Potential: CBN’s ability to inhibit the proliferation of neuroblastoma cells has been studied, demonstrating its potential in the fight against cancer. (See the study.)

For those seeking a natural solution for sleep issues, CBN may be an appealing option to consider.

CBG: The Mother of All Cannabinoids with Great Potential

CBG (cannabigerol) is a fundamental component of cannabis chemistry, acting as a precursor to other cannabinoids. As the plant matures, CBG converts into THC, CBD, and CBC, so CBG-rich strains should be harvested early.

CBG is non-psychoactive, and its effects have been studied for their potential to treat various conditions:

Anti-Inflammatory Effect: CBG effectively reduces inflammation and shows promise in alleviating symptoms of inflammatory bowel disease (IBD). (See the study.)
Neuroprotective Effect: The protective effects of CBG on neurons are being actively investigated. Its anti-inflammatory properties in the central nervous system could be crucial for managing neuroinflammation, especially in diseases like multiple sclerosis. (See the study.)
Appetite Stimulant: Unlike THCV, CBG may stimulate appetite, making it a candidate for managing eating disorders or unintended weight loss.

CBG-rich cannabis strains are an excellent option for those seeking the therapeutic benefits of cannabis without psychoactive effects.

Unique Mechanism of Action

CBG is believed to bind to vanilloid receptors, which are involved in pain signal transmission within the central nervous system. By interacting with these receptors, CBG may produce calming effects.

The Difficulty and Cost of CBG Extraction

Despite its promising benefits, the extraction and isolation of CBG from hemp plants is an expensive and complex process.

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Liz Filmer