CBD could be a Therapeutic Option for Rheumatoid Arthritis?

Liz Filmer
05 Sep 2025

New research shows that a CBD extract could modulate inflammation and reduce pain in people with rheumatoid arthritis. CBD may be an important ally in managing rheumatoid arthritis.


This is according to a new study published in the journal "Frontiers in Immunology," which showed that a particular cannabis extract high in cannabidiol (CBD), called "CBD-X," could become an important therapeutic option.

It is a chronic autoimmune disease that severely impacts daily life, causing pain, stiffness, and progressive joint damage, which can lead to disability. It is a complex and costly disease for the healthcare system, which continues to pose a medical challenge.

Research, conducted on animal models, has demonstrated that CBD-X can directly intervene in the inflammatory process of the disease. Researchers observed that the extract reduced the production of molecules that trigger inflammation, such as the cytokine TNF-α, often at the centre of rheumatoid arthritis medications.

Moreover, treatment with CBD-X was also shown to reduce the presence of certain immune system cells (neutrophils and monocytes) that are responsible for joint tissue damage. Essentially, the extract helped the body "reorganise" its immune response, reducing the attack on its own joints and promoting cells that help resolve inflammation.

These results are particularly significant because CBD-X did not simply suppress symptoms but also had a more profound effect on the disease. This dual-action approach opens new avenues in drug research and development. Although research is still in its early stages and human clinical trials are needed, evidence suggests that CBD-X has great potential as a therapeutic agent, offering hope for millions of people living with rheumatoid arthritis worldwide.

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Liz Filmer