Unlocking the Potential of Cannabis Leaves: Insights from a Study on Phenols
Phenols are known for their strong antioxidant properties
Cannabis leaves are often thrown away, seen as waste. However, recent research from South Africa suggests that these leaves may actually contain valuable compounds. Researchers from Stellenbosch University’s Department of Chemistry and Polymer Science conducted a detailed analysis of cannabis phenols, commonly found compounds in plants.
Their findings were published in the Journal of Chromatography A. "While much has been studied about cannabinoids and terpenoids, we’ve paid little attention to the phenolic composition of cannabis," the researchers noted. "Given that previous studies have shown beneficial interactions within cannabis, it’s becoming more important to look at polyphenols." Phenols, or phenolic compounds, are known for their strong antioxidant properties, which help protect our cells from damage caused by free radicals.
What are the Benefits of Phenols?
They also have anti-inflammatory and antimicrobial benefits, making them useful for treating infections and inflammation. Many of these compounds, such as flavonoids, play a role in preventing chronic diseases like heart disease, cancer, and neurodegenerative disorders. Some specific phenols, like salicylic acid, are used in medicines or topical treatments for their healing properties.
In the study, researchers found three types of C-glycosylated flavones and several of their O-glycosylated forms, which helped distinguish one cannabis variety from others. They also detected flavone alkaloids in the same strain, mainly from the leaves. Although they couldn't precisely define the structures of these compounds, they were able to identify four categories of flavonoid alkaloids consisting of 16 different derivatives. "This is the first time we've discovered this interesting and rare class of compounds in cannabis. It highlights the diversity within the plant," the researchers concluded. This study demonstrates that there is still a lot to learn about cannabis, especially regarding its leaves and other parts of the plant.
"Our research showcases the medicinal potential of cannabis plant material that is often discarded. Cannabis has a unique and rich profile of non-cannabinoid phenolics, which could be important for medical research," explained Professor André de Villiers, a co-author of the study. Overall, it's clear that more research on cannabis is needed, and we can look forward to exciting discoveries in the future.
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Liz Filmer
