Cannabis and Medication Interactions
Understand how cannabis interacts with other drugs to use it safely.
More people are using medical cannabis, raising concerns about its safety, especially when taken with other medications. Mixing substances can lead to unexpected problems, such as reducing how well medications work or increasing their side effects. It’s important to understand how cannabis interacts with other drugs to use it safely.
How Cannabis Interacts with Medications
To understand why cannabis affects other medications, we need to know about the cytochrome P450 system. This group of enzymes, mainly found in the liver, helps process over 60% of the medications we take.
Cannabinoids, especially CBD, can slow down these enzymes. When you consume CBD, it may take longer for the body to eliminate other medications. This can increase the level of these drugs in the blood, raising the risk of side effects or overdose.
Common Medication Interactions
Research shows that cannabis can interact with different types of medications. The level of interaction depends on the amount of cannabis used, how often it is taken, the type of cannabinoid (THC or CBD), and the specific medication.
Anticoagulants: CBD can slow down the enzymes that break down anticoagulants like warfarin, which may increase bleeding risks.
Antidepressants: Using cannabis with some antidepressants, especially SSRIs (selective serotonin reuptake inhibitors), may cause drowsiness or increased sedation.
Anxiolytics and Sedatives: Cannabis can enhance the effects of benzodiazepines, leading to more sedation and decreased responsiveness.
Consult Your Doctor
Evidence shows that cannabis can interact with other medications, so it’s vital to be cautious. While cannabis can offer benefits, combining it with other medications should only be done under a healthcare professional's guidance.
To stay safe, tell your doctor if you plan to use cannabis. A healthcare provider can adjust your medication, monitor your progress, and ensure your safety. This article is for informational purposes and does not replace professional medical advice.
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Liz Filmer
